Download PDFOpen PDF in browserUnleashing Guardians: Exploring the Therapeutic Potential of Gamma Delta T Cells in HIV ControlEasyChair Preprint 124354 pages•Date: March 10, 2024AbstractHuman immunodeficiency virus (HIV) remains a global health challenge, necessitating continuous exploration of innovative therapeutic strategies. This research investigates the adoptive transfer of allogeneic gamma delta (γδ) T cells and its impact on HIV replication using a humanized mouse model. The study aims to elucidate the potential risks and benefits associated with this therapeutic approach, focusing on its impact on viral load, immune response, and overall host health. Human Immunodeficiency Virus (HIV) remains a global health challenge, necessitating innovative approaches to combat the virus and improve treatment outcomes. This research paper explores the potential role of gamma-delta (γδ) T cells in the control of HIV, focusing on the lesser-known aspects of their function and their untapped therapeutic potential. The paper reviews existing literature on γδ T cells, their unique features, and their ability to bridge innate and adaptive immune responses. Furthermore, the study investigates recent advancements in understanding the elusive characteristics of these cells and their potential in HIV control. The findings suggest that harnessing the power of γδ T cells may open new avenues for therapeutic interventions in HIV and contribute to the development of more effective and targeted treatment strategies. Keyphrases: Gamma-Delta T Cells, HIV Control, Therapeutic potential
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