Download PDFOpen PDF in browserAdvancements in Humanized Mouse and Rat Models for HIV Research: from Conventional Approaches to Innovative StrategiesEasyChair Preprint 123494 pages•Date: March 1, 2024AbstractIn the realm of HIV research, humanized mouse and rat models have evolved into essential tools, serving as crucial bridges between in vitro studies and clinical trials. This article delves into the current landscape of these models, emphasizing their pivotal role in exploring preventive and curative strategies against HIV infection and related pathologies. The discussion encompasses diverse methodologies employed for the humanization of these animal models, addresses encountered challenges, and introduces emerging techniques that hold promise for advancing HIV research. Through an examination of the strengths and limitations of existing models, this article aims to guide researchers toward more effective strategies in the ongoing battle against HIV/AIDS. Keyphrases: HIV Research, Humanized Mouse, Mouse and Rat Models
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