Progress in Preclinical Research: Enhanced Mouse and Rat Models Featuring Complete Human Skin and Autologous Immune Cells

EasyChair Preprint 12301

Abstract

The utilization of animal models in biomedical research has played a crucial role in advancing our comprehension of human physiology, disease mechanisms, and therapeutic strategies. Nevertheless, disparities between human and animal immune systems present challenges in accurately predicting human-specific responses to diseases and treatments. A noteworthy advancement in addressing this issue is the creation of humanized mouse and rat models, integrating full-thickness human skin and autologous immune cells. This paper delves into the methodology, applications, and potential ramifications of these sophisticated models in the realm of preclinical research and drug development.

Keyphrases: Human skin, Preclinical research, Rat Models

@booklet{EasyChair:12301,
  author    = {Rohit Mishra},
  title     = {Progress in Preclinical Research: Enhanced Mouse and Rat Models Featuring Complete Human Skin and Autologous Immune Cells},
  howpublished = {EasyChair Preprint 12301},
  year      = {EasyChair, 2024}}