The BLT Humanized Mouse Model as a Tool for Studying Human Gamma Delta T Cell-HIV Interactions in Vivo

EasyChair Preprint 12348

Abstract

The BLT (bone marrow, liver, thymus) humanized mouse model has emerged as a valuable tool for investigating the interactions between human gamma delta (γδ) T cells and Human Immunodeficiency Virus (HIV) in an in vivo setting. This research paper aims to comprehensively review the current state of knowledge regarding the BLT humanized mouse model, emphasizing its utility in unraveling the intricate dynamics between γδ T cells and HIV. The paper will delve into the construction of the BLT model, its advantages and limitations, and the pivotal insights it has provided into the interplay between γδ T cells and HIV pathogenesis.

Keyphrases: Gamma Delta T Cell, HIV Interactions, Humanized mouse model

@booklet{EasyChair:12348,
  author    = {Saba Shehzadi},
  title     = {The BLT Humanized Mouse Model as a Tool for Studying Human Gamma Delta T Cell-HIV Interactions in Vivo},
  howpublished = {EasyChair Preprint 12348},
  year      = {EasyChair, 2024}}