Download PDFOpen PDF in browserTransitioning of Humanized Mouse and Rat Models from Traditional Approaches to Innovative StrategiesEasyChair Preprint 125594 pages•Date: March 18, 2024AbstractIn the realm of HIV research, humanized mouse and rat models have emerged as essential tools, serving as vital links between in vitro studies and clinical trials. This article delves into the present state of these models, emphasizing their critical roles in exploring preventive and therapeutic approaches against HIV infection and related ailments. The discourse covers diverse methodologies utilized for humanizing these animal models, discusses challenges encountered, and introduces promising emerging techniques that are propelling HIV research forward. Through an analysis of the strengths and weaknesses of current models, this article seeks to guide researchers towards more efficient strategies in the continual battle against HIV/AIDS. Keyphrases: HIV, Humanized skin, Rat and Cat Model
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