Assessing Tumor Invasion Depth and Extramural Vascular Invasion with DWI

EasyChair Preprint 14165

Abstract

Accurate staging of colorectal cancer is crucial for guiding treatment decisions and improving patient outcomes. Conventional imaging modalities, such as computed tomography (CT) and magnetic resonance imaging (MRI), have limitations in accurately assessing the depth of tumor invasion and the presence of extramural vascular invasion (EMVI). These factors are essential for determining the appropriate treatment approach, as they influence the risk of local recurrence and the need for neoadjuvant therapy.
Diffusion-weighted imaging (DWI) has emerged as a promising tool in the preoperative staging of colorectal cancer. DWI provides information about the microscopic movement of water molecules within tissues, which can be influenced by the density and organization of cellular structures. In the context of colorectal cancer, the distinct DWI signal characteristics of the tumor and surrounding tissues have been shown to correlate with the depth of tumor invasion and the presence of EMVI.
This review will explore the role of DWI in assessing tumor invasion depth and EMVI in colorectal cancer, highlighting the advantages and limitations of this imaging technique compared to conventional modalities. The discussion will focus on the underlying principles of DWI, the correlation between DWI findings and pathological staging, and the potential clinical impact of incorporating DWI into the preoperative assessment of colorectal cancer.

Keyphrases: cancer, citations, health sciences

@booklet{EasyChair:14165,
  author    = {Joseph Bayo Shalom},
  title     = {Assessing Tumor Invasion Depth and Extramural Vascular Invasion with DWI},
  howpublished = {EasyChair Preprint 14165},
  year      = {EasyChair, 2024}}