Pro-Drugs and Drug Delivery Systems

EasyChair Preprint 15058

Abstract

Pro-drugs and drug delivery systems are vital advancements in pharmaceutical research aimed at enhancing the efficacy, safety, and patient compliance of therapeutics. Pro-drugs are biologically inactive compounds that undergo metabolic conversion within the body to release an active drug. This approach optimizes drug properties such as solubility, bioavailability, and targeted delivery, minimizing side effects. Drug delivery systems (DDS), on the other hand, involve various strategies like nanoparticles, liposomes, and polymer-based carriers to control the release and localization of drugs, improving therapeutic outcomes. Together, pro-drugs and advanced DDS play a significant role in precision medicine, offering new frontiers for treating diseases with increased specificity and reduced systemic toxicity. This review highlights key developments in pro-drug design and DDS technologies, their mechanisms, and future trends in personalized healthcare.

Keyphrases: Aurora kinase, BET, CDK, CDK9, cancer, computer-aided drug design, dual inhibitor, inhibitor, kinase

@booklet{EasyChair:15058,
  author    = {Kaledio Potter and Axel Egon and Abram Gracias},
  title     = {Pro-Drugs and Drug Delivery Systems},
  howpublished = {EasyChair Preprint 15058},
  year      = {EasyChair, 2024}}